Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep622 | Obesity and cardiovascular endocrinology | ECE2015

Increased FNDC5 (irisin) expression in subcutaneous adipose tissue in obese patients with type 2 diabetes 1 year after bariatric surgery

Muenzker Julia , Harger Alexandra , Tuca Alexandru , Lindheim Lisa , Zachhuber Verena , Svehlikova Eva , Freisinger Oana , Fruhmann Johanna , Tadler Friedrich , Pieber Thomas R , Obermayer-Pietsch Barbara

Aim: Gastric bypass surgery improves glycaemic control, but the underlying mechanisms including potential changes in adipoinsular axis are incompletely understood. The aim of this study was to investigate potentially causal or associated alterations in gene expression of adipokines, myokines, and hormones in the subcutaneous and visceral adipose tissue of diabetic and non-diabetic obese subjects before and after gastric bypass.Material and methods: Biops...